N-acetylcysteine (NAC) supplements are the synthetic form of the amino acid cysteine. Cysteine is a non-essential (or semi-essential) amino acid. This means your body produces some of what you need, and you also get some from food. There are several claims about the benefits of NAC supplements for certain health conditions, like respiratory diseases, heart disease, and mental health disorders.
Some research suggests NAC supplements can increase the amount of glutathione in your body. Glutathione is a powerful antioxidant. NAC bonds with two other amino acids—glutamine and glycine- to create it. Due to NAC's antioxidant and anti-inflammatory characteristics, it has been used in clinical practice for people hospitalized with COVID-19. A 2021 study published in Infectious Diseases looked at the effects of NAC supplementation. Researchers said taking 600 mg NAC orally (by mouth) twice daily for 14 days led to reduced disease progression, reduced need for intubation (a breathing tube), fewer deaths.
The novel coronavirus disease (COVID-19) is caused by a virus (SARS-Cov-2) and is known for inducing multisystem organ dysfunction associated with significant morbidity and mortality. Current therapeutic strategies for COVID-19 have failed to reduce the mortality rate, especially for elderly patients effectively. Exploring new applications of existing medications could potentially provide valuable treatments for COVID-19. N-acetylcysteine (NAC) has been used in clinical practice to treat critically ill septic patients and, more recently, for COVID-19 patients. NAC has antioxidant, anti-inflammatory, and immune-modulating characteristics that may prove beneficial in treating and preventing SARS-Cov-2. This review offers a thorough analysis of NAC and discusses its potential use for the treatment of COVID-19.
Foods Packed with NAC
NAC can be found in many local foods. Products such as cheese (especially ricotta), eggs and yogurt also contain high levels of NAC. Additionally, NAC is also found in broccoli, bananas, onions, red peppers, garlic, and soy beans.
Dosage of NAC
Most NAC supplements are sold in 500 mg dosages, although some are as high as 1,200 mg. Product suggested doses range from 1 to 4 doses per day, for a total of 500 mg to 3,000 mg daily. However, since the FDA does not regulate supplements, NAC does not have universal guidelines for its use. Therefore, use caution and work with a qualified healthcare provider when considering this (and any) supplement.
Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The contents of this website are based upon the views of Dr. Walker and his experience. This product is not intended as medical advice nor to diagnose, treat, cure or prevent any disease. The information is likewise not to replace the advice of a qualified health care provider. The information provided herein is intended as a sharing of general knowledge only and is not intended to be, nor is it, medical advice or a substitute for medical advice. That being said, please consult your healthcare provider before using supplements or providing supplements to children under the age of 18. If you have or suspect you have, a specific medical condition or disease, please consult your healthcare provider.
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