What is Hypothyroidism?
Hypothyroidism is a medical condition characterized by an underactive thyroid gland, which fails to produce sufficient amounts of thyroid hormones. The thyroid is a butterfly-shaped gland located at the front of the neck and plays a crucial role in regulating various bodily functions, including metabolism, energy production, temperature regulation, and overall growth and development. The most common cause of hypothyroidism in the United States is Hashimoto’s thyroiditis, also called chronic lymphocytic thyroiditis and chronic autoimmune thyroiditis. Hashimoto results from the gland making and releasing too little thyroid hormone and has a strong association with lymphoma. Autoimmune thyroid diseases are the leading causes of hypothyroidism with the disease being more common among people older than age 60. Women are also much more likely than men to develop hypothyroidism. Hypothyroidism can manifest through a variety of symptoms that can vary in severity and may develop gradually over time.
What are Some Common Symptoms?
➢ Fatigue: Persistent tiredness or lack of energy is one of the most common symptoms.
➢ Weight Gain: Unexplained weight gain or difficulty losing weight, despite a healthy diet and exercise, can occur due to a slowed metabolism.
➢ Cold Intolerance: Increased sensitivity to cold temperatures is common, as the body may struggle to regulate temperature.
➢ Dry Skin and Hair: Skin may become dry and rough, and hair may become brittle, leading to hair loss or thinning.
➢ Constipation: Slowed digestive processes can lead to constipation.
➢ Depression: Hypothyroidism can contribute to feelings of sadness, depression, or anxiety.
➢ Memory Problems: Difficulty concentrating or memory issues may occur, often described as "brain fog."
➢ Muscle Weakness or Cramps: Some individuals may experience muscle weakness, cramps, or stiffness.
➢ Slow Heart Rate: A lower than normal heart rate (bradycardia) can occur in some patients.
➢ Hoarseness: Changes in voice, such as hoarseness, may develop.
➢ Swelling: Puffiness in the face, particularly around the eyes, and swelling in the hands and feet can occur.
➢ Menstrual Irregularities: Women may experience heavier, more frequent menstrual periods or irregular cycles.
➢ Goiter: An enlargement of the thyroid gland may be visible at the base of the neck, although this is not always present.
How Does Fluoride Affect the Thyroid?
Fluoride and iodine interact in complex ways that can affect thyroid function and iodine metabolism. Here are some key points regarding how fluoride can impact iodine levels and thyroid health:
✓ Inhibition of Iodine Uptake:
o Fluoride can compete with iodine for uptake in the thyroid gland. When fluoride is present in higher concentrations, it can inhibit the transport of iodine into the thyroid cells, potentially leading to reduced synthesis of thyroid hormones.
✓ Thyroid Hormone Production:
o Studies suggest that excessive fluoride exposure may impair the production of thyroid hormones by reducing iodine availability. This can lead to an increased risk of hypothyroidism, especially in individuals who already have low iodine levels.
✓ Goitrogenic Effect:
o Fluoride has been suggested to have goitrogenic properties, meaning it can contribute to the development of goiter (enlargement of the thyroid gland) by disrupting normal thyroid function. This effect is particularly relevant in areas where iodine deficiency is already a concern.
✓ Environmental and Dietary Factors:
o In regions where both fluoride exposure and iodine deficiency are prevalent, the risk of thyroid dysfunction may be compounded. For example, communities that rely on fluoridated water may have an increased risk of thyroid issues if their diets are low in iodine.
✓ Research Findings:
o Some studies have indicated a correlation between high fluoride exposure and increased rates of hypothyroidism and goiter, particularly in populations with low iodine intake.
✓ Public Health Considerations:
- Public health guidelines emphasize the importance of maintaining adequate iodine intake, especially in areas with high fluoride exposure. Ensuring sufficient iodine levels can help mitigate potential negative effects associated with fluoride.
Common Causes of Hypothyroidism:
Some of the Most Common Causes:
❖ Fluoride and Tap Water: Fluoride competes with iodine for uptake in the thyroid gland. When fluoride is present it inhibits the transport of iodine into the thyroid cells, leading to reduced synthesis of thyroid hormones. Studies suggest that excessive fluoride exposure may impair the production of thyroid hormones and can lead to an increased risk of hypothyroidism. Fluoride can contribute to the development of goiter (enlargement of the thyroid gland) by disrupting normal thyroid function.
❖ Hashimoto's Thyroiditis: This is the most prevalent cause of hypothyroidism. It is an autoimmune condition where the body's immune system attacks the thyroid gland, leading to inflammation and decreased production of thyroid hormones.
❖ Thyroid Surgery: Surgical removal of all or part of the thyroid gland (thyroidectomy) can result in hypothyroidism, especially if a significant portion is removed.
❖ Radiation Therapy: Treatments for cancers of the head, neck, or thyroid itself using radiation can damage the thyroid gland and result in hypothyroidism.
❖ Medications: Certain medications can affect thyroid function, including:
- Lithium: Often used to treat bipolar disorder, lithium can interfere with thyroid hormone production.
- Amiodarone: A medication used to treat irregular heartbeats, it can also affect thyroid function.
- Antithyroid medications: Used to treat hyperthyroidism, these can sometimes lead to hypothyroidism.
❖ Iodine Deficiency: Iodine is essential for the production of thyroid hormones. A deficiency can lead to decreased hormone production and hypothyroidism. This is less common in developed countries due to iodized salt.
❖ Congenital Hypothyroidism: Some babies are born with a non-functioning or absent thyroid gland, leading to hypothyroidism from birth.
❖ Pituitary Disorders: The pituitary gland produces thyroid-stimulating hormone (TSH), which regulates the thyroid. If the pituitary gland is not functioning properly (due to a tumor or other condition), it may not produce enough TSH, leading to low thyroid hormone levels.
❖ Thyroiditis: Inflammation of the thyroid gland (not necessarily autoimmune) can lead to temporary or permanent hypothyroidism. Conditions such as subacute thyroiditis or postpartum thyroiditis can cause transient hypothyroidism.
❖ Aging: The risk of hypothyroidism increases with age, and some older adults may develop the condition due to natural changes in thyroid function.
❖ Other Autoimmune Diseases: Individuals with other autoimmune disorders (such as type 1 diabetes, rheumatoid arthritis, or lupus) are at a higher risk of developing hypothyroidism
Four Different Types of Hypothyroidism:
Primary Hypothyroidism:
o Definition: This is the most common type of hypothyroidism, occurring when the thyroid gland itself is unable to produce sufficient amounts of thyroid hormones (T3 and T4).
o Causes: Common causes include autoimmune conditions like Hashimoto's thyroiditis, iodine deficiency, thyroid surgery, radiation therapy, or congenital conditions where the thyroid gland is absent or underdeveloped.
Secondary Hypothyroidism:
o Definition: This type occurs when the pituitary gland fails to produce enough thyroid-stimulating hormone (TSH), which is necessary for stimulating the thyroid gland to produce hormones.
o Causes: Causes can include pituitary tumors, pituitary damage from surgery or radiation, or conditions that affect the pituitary gland, such as Sheehan's syndrome (postpartum pituitary gland failure).
Tertiary Hypothyroidism:
o Definition: Tertiary hypothyroidism arises from a failure of the hypothalamus to produce thyrotropin-releasing hormone (TRH), which signals the pituitary gland to produce TSH.
o Causes: This can be due to hypothalamic disorders, tumors, or damage from surgery or radiation that affects the hypothalamus.
Congenital Hypothyroidism:
o Definition: This type is present at birth and results from the thyroid gland not developing properly or not functioning adequately.
o Causes: Congenital hypothyroidism can be due to genetic factors, developmental issues during pregnancy, or maternal iodine deficiency. It is often screened for in newborns to ensure timely treatment.
A few Natural Remedies:
Here are some natural ways that may help support thyroid function:
▪ Balanced Diet:
Iodine: Ensure you get enough iodine, as it is crucial for the production of thyroid hormones. Good sources include iodized salt, fish, A2 dairy, and seaweed.
Selenium: This mineral is vital for the conversion of T4 (inactive) to T3 (active) thyroid hormone. Foods rich in selenium include Brazil nuts, fish, and mushrooms.
Zinc: This mineral is also important for thyroid health. Sources include shellfish, nuts, and A2 dairy.
Iron: Low iron levels can affect thyroid function. Include iron-rich foods like seafood and spinach.
Vitamin D: Adequate levels of vitamin D may support thyroid function. You can get vitamin D through sunlight exposure, fatty fish, and supplements.
▪ Avoid Goitrogens: Goitrogens are substances that can interfere with thyroid hormone production. They are found in certain raw cruciferous vegetables (like broccoli, cauliflower, and kale) and soy products. Cooking these foods can help reduce their goitrogenic effects, but if you have thyroid issues, you might want to consume them in moderation.
▪ Regular Exercise: Engaging in regular physical activity can help boost metabolism and support overall endocrine function, including the thyroid. Aim for a mix of aerobic exercises, strength training, and flexibility workouts.
▪ Manage Stress: Chronic stress can negatively impact thyroid function. Incorporating stress-reducing techniques such as mindfulness, meditation, yoga, deep breathing exercises, or other relaxation practices can be beneficial.
▪ Get Enough Sleep: Quality sleep is crucial for hormonal balance and overall health. Aim for 7-9 hours of restorative sleep each night.
▪ Stay Hydrated: Ensure you drink enough water. Dehydration can affect metabolism and overall health.
▪ Limit Sugar. The Relationship Between Hypothyroidism and Sugar Consumption:
o Metabolic Slowdown: Hypothyroidism often results in a slower metabolism, which can lead to weight gain or difficulty losing weight. Consuming excess sugar can exacerbate these issues by providing empty calories that contribute to weight gain without nutritional benefits.
o Blood Sugar Regulation: Individuals with hypothyroidism may experience difficulty regulating blood sugar levels. This can lead to fluctuations in energy levels, mood swings, and cravings for sugary foods. Consuming high amounts of sugar can worsen these effects and contribute to insulin resistance over time.
o Increased Cravings: Many people with hypothyroidism report increased cravings for carbohydrates and sugars. This can be due to hormonal imbalances and the body's need for quick energy, which can lead to overeating or unhealthy dietary choices.
o Impact on Energy Levels: Since hypothyroidism can cause fatigue and decreased energy levels, individuals may turn to sugary foods and beverages for a quick energy boost. However, this can lead to subsequent crashes in energy levels, perpetuating a cycle of fatigue and reliance on sugar.
o Inflammation: A diet high in sugar can increase inflammation in the body. Since hypothyroidism is often associated with inflammatory conditions (such as autoimmune thyroiditis), consuming excess sugar may exacerbate inflammation and worsen symptoms.
Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The contents of this website are based upon the views of Dr. Walker and his experience. This product is not intended as medical advice nor to diagnose, treat, cure or prevent any disease. The information is likewise not to replace the advice of a qualified health care provider. The information provided herein is intended as a sharing of general knowledge only and is not intended to be, nor is it, medical advice or a substitute for medical advice. That being said, please consult your healthcare provider before using supplements or providing supplements to children under the age of 18. If you have or suspect you have, a specific medical condition or disease, please consult your healthcare provider.
© Dr. Dennis D. Walker 2022. All Rights Reserved