Pernicious Anemia


Pernicious anemia is a cause of vitamin B12 deficiency anemia. Almost 50% of adults with a vitamin B-12 deficiency may have pernicious anemia. This type of anemia is caused by an autoimmune process that makes a person unable to produce a specific and essential substance in the stomach which is called an intrinsic factor. Importantly, people with pernicious anemia are unable to make enough red blood cells. Despite this, a person could have pernicious anemia for several years before noticing changes in their body. If left untreated, however pernicious anemia can cause serious medical issues as well as several chronic digestive disorders.

What is Pernicious Anemia a Problem?

In the body, several vitamins are ingested and this includes vitamin B12. But when the stomach is unable to produce the intrinsic factor that is necessary to absorb dietary vitamin B12 in the small intestine. This nutrient is essential for the adequate production of red blood cells as well as the body function.

What are the Risk Factors for Pernicious Anemia?

Pernicious anemia is associated with an autoimmune inflammation in the stomach. It also involves the inability to absorb vitamin B12 in the small intestine.

What are the Common Symptoms of Pernicious Anemia?

Pernicious anemia comprises many symptoms some of which include:
a) Chest pain
b) Diarrhea
c) Fatigue
d) Loss of appetite
e) Poor concentration
f) Shortness of breath
g) Swollen tongue

What are the Long-term Problems with Pernicious Anemia?

• Confusion
• Memory loss
• Balancedisorders
• Numbness /tingling in hands and feet
• Problems concentrating
• Irritability
• Hallucinations
• Optic nerve damage

What are the Common Causes of Pernicious Anemia?

Pernicious anemia arises from:
• Autoimmune condition: Thai condition results in the body's immune system attacking cells in the lining of the stomach.
• Genetics
• Weakened stomach lining

Can Pernicious Anemia Be Prevented?

No, you cannot prevent pernicious anemia from occurring but you can reduce your risk of having the condition. This can be done by being aware of the medical condition, treatment, and activities as well as how your body will be affected by it.
You can also incorporate the following:
1) Iron: The consumption of iron-rich food like fish, and beans can be combined with vitamin C-rich food to enhance iron absorption.
2) Folate: The body requires sufficient folate to absorb vitamin B12. This can be obtained from leafy green vegetables, avocados, and fruits.
3) Vitamin B12: You can increase the vitamin B12 in the body by consuming shellfish, fish eggs, and dairy products in your diet.
4) Vitamin C: Increasing your intake of food rich in vitamin C like strawberries, and kiwi, assists in iron absorption and supports the overall immune health.

How is Pernicious Anemia Diagnosed?

Pernicious anemia can be diagnosed with severe tests. Some of these tests include;
• Complete Blood Count:Pernicious anemia can be screened for using hemoglobin and hematocrit levels.
• Vitamin B12 Level: The doctor can carry out a blood test to assess the vitamin B12 level via a blood test. When the level of vitamin B12 is below normal, it indicates a deficiency.
• Intrinsic Factor and Parietal Cells Antibodies: This is a blood test that involves the screening of antibodies against intrinsic factors and the parietal cells of the stomach.


References:

https://my.clevelandclinic.org/health/diseases/22377-pernicious-anemia
https://www.healthline.com/health/pernicious-anemia#What-is-pernicious-anemia?
https://www.pennmedicine.org/for-patients-and-visitors/patient-information/conditions-treated-a-to-z/pernicious-anemia




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Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The contents of this website are based upon the views of Dr. Walker and his experience. This product is not intended as medical advice nor to diagnose, treat, cure or prevent any disease. The information is likewise not to replace the advice of a qualified health care provider. The information provided herein is intended as a sharing of general knowledge only and is not intended to be, nor is it, medical advice or a substitute for medical advice. That being said, please consult your healthcare provider before using supplements or providing supplements to children under the age of 18. If you have or suspect you have, a specific medical condition or disease, please consult your healthcare provider.

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